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UBE2D2 (基因名), Ubiquitin-conjugating enzyme E2 D2 (蛋白名), ub2d2_bovin.
产品名称:

Bovine UBE2D2/ Ubiquitin-conjugating enzyme E2 D2 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

(E3-independent) E2 ubiquitin-conjugating enzyme D2, E2 ubiquitin-conjugating enzyme D2, Ubiquitin carrier protein D2, Ubiquitin-protein ligase D2, UBC4, UBCH4, UBCH5B

检测方法:
ELISA
特异性:
Natural and recombinant bovine Ubiquitin-conjugating enzyme E2 D2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Bovine UBE2D2 ELISA Kit
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Bovine UBE2D2 ELISA Kit
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产品说明书
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通用注释


亚单元:
Interacts with SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex. Interacts with CNOT4 (via RING domain). Interacts with E3 ubiquitin-protein ligases CBLC, PJA1 and PJA2. Interacts with PDZRN3.


功能:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.


亚细胞位置:
N/A


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