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USP16 (基因名), Ubiquitin carboxyl-terminal hydrolase 16 (蛋白名), ubp16_bovin.
产品名称:

Bovine USP16/ Ubiquitin carboxyl-terminal hydrolase 16 ELISA Kit

货号:

E11580b

商标:
EIAab®
监管等级:
别名:

Deubiquitinating enzyme 16, Ubiquitin thioesterase 16, Ubiquitin-specific-processing protease 16

检测方法:
ELISA
特异性:
Natural and recombinant bovine Ubiquitin carboxyl-terminal hydrolase 16
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Bovine USP16 ELISA Kit
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Bovine USP16 ELISA Kit
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通用注释


亚单元:
Homotetramer.


功能:
Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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