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UCP1 (基因名), Mitochondrial brown fat uncoupling protein 1 (蛋白名), ucp1_canlf.
产品名称:

Dog UCP1/ Mitochondrial brown fat uncoupling protein 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Solute carrier family 25 member 7, Thermogenin, UCP 1, SLC25A7

检测方法:
ELISA
特异性:
Natural and recombinant dog Mitochondrial brown fat uncoupling protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cardiovascular
Dog UCP1 ELISA Kit
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Dog UCP1 ELISA Kit
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通用注释


亚单元:
Most probably functions as a monomer. Binds one purine nucleotide per monomer. However, has also been suggested to function as a homodimer or a homotetramer. Tightly associates with cardiolipin in the mitochondrion inner membrane; may stabilize and regulate its activity.


功能:
Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.


亚细胞位置:
Mitochondrion inner membrane Multi-pass membrane protein


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