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UXT (基因名), Protein UXT (蛋白名), uxt_bovin.
产品名称:

Bovine UXT/ Protein UXT ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Ubiquitously expressed transcript protein

检测方法:
ELISA
特异性:
Natural and recombinant bovine Protein UXT
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Bovine UXT ELISA Kit
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Bovine UXT ELISA Kit
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亚单元:
Homohexamer. Interacts with LRPPRC. Interacts with AR N-terminus. In the nucleus interacts specifically with RELA and forms a dynamic complex with NF-kappa-B and is recruited to the NF-kappa-B enhanceosome upon stimulation. Interacts with MECOM and URI1.


功能:
Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor (AR) transcription. AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation. Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling. Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC. May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function. Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM. Together with URI1, associates with chromatin to the NKX3-1 promoter region.


亚细胞位置:
Cytoplasm Cytoplasm Cytoskeleton Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Nucleus


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