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WASHC2C (基因名), WASH complex subunit 2C (蛋白名), wac2c_human.
产品名称:

Human WASHC2C/ WASH complex subunit 2C ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Vaccinia virus penetration factor, VPEF, FAM21C, KIAA0592, VPEF

检测方法:
ELISA
特异性:
Natural and recombinant human WASH complex subunit 2C
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human WASHC2C ELISA Kit
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Human WASHC2C ELISA Kit
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产品说明书
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通用注释


亚单元:
Component of the WASH core complex also described as WASH regulatory complex (SHRC) composed of WASH (WASHC1, WASH2P or WASH3P), WASHC2 (WASHC2A or WASHC2C), WASHC3, WASHC4 and WASHC5; in the complex interacts (via N-terminus) directly with WASHC1. The WASH core complex associates via WASHC2 with the F-actin-capping protein dimer (formed by CAPZA1, CAPZA2 or CAPZA3 and CAPZB) in a transient or substoichiometric manner which was initially described as WASH complex (PubMed:19922875, PubMed:20498093). Interacts with VPS35; mediates the association with the retromer CSC complex. Interacts with FKBP15. Interacts with CCDC93, CCDC22, VPS35L; indicative for an association of the WASH core complex with the CCC and retriever complexes. May directly interact with TBC1D23 (Probable).


功能:
(Microbial infection) Plays a role in fluid-phase endocytosis, a process exploited by vaccinia intracellular mature virus (IMV) to enter cells. As a result, may facilitate the penetration of IMV into cells.


亚细胞位置:
Early endosome membrane Cell membrane Partially colocalizes with RAB11A, a recycling endosome marker. Associates with lipid raft microdomains on the plasma membrane.


该产品尚未在任何出版物中被引用。
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