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Ythdc1 (基因名), YTH domain-containing protein 1 (蛋白名), ytdc1_mouse.
产品名称:

Mouse Ythdc1/ YTH domain-containing protein 1 ELISA Kit
YTH结构域蛋白1

货号:

E7767m

商标:
EIAab®
监管等级:
别名:

Kiaa1966

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.075ng/mL
特异性:
Natural and recombinant mouse YTH domain-containing protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Epigenetics
Mouse Ythdc1 ELISA Kit
规格 & 价格: cart
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Mouse Ythdc1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with KHDRBS1/SAM68 (By similarity). Interacts with SRSF1 (By similarity). Interacts with SRSF2 (By similarity). Interacts with TRA2B (By similarity). Interacts with SRSF3 (By similarity). Interacts with SRSF10 (By similarity). Interacts with KHDRBS3 (By similarity). Interacts with EMD (By similarity). Interacts with RBMX.


功能:
Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a key regulator of exon-inclusion or exon-skipping during alternative splicing via interaction with mRNA splicing factors SRSF3 and SRSF10. Specifically binds m6A-containing mRNAs and promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. In contrast, interaction with SRSF3 prevents interaction with SRSF10, a splicing factor that promotes exon skipping: this prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing. May also regulate alternative splice site selection.


亚细胞位置:
Nucleus Nucleus speckle Localizes to a novel subnuclear structure, the YT bodies.


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