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A2M (基因名), Alpha-2-macroglobulin (蛋白名), a2mg_human.
产品名称:

A2M Antibody
α-2巨球蛋白

货号:

M1017Rb-h

商标:
EIAab®
监管等级:
别名:

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, FWP007, Alpha-2-M, CPAMD5

反应性:
human
免疫原:
Recombinant human A2M protein ( R1017h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Monoclonal
亚型:
Mouse IgG
应用:
推荐产品:
研究领域:
-
  • Human A2M Monoclonal Antibody
  • Human A2M Monoclonal Antibody
  • Human A2M Monoclonal Antibody
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通用注释


亚单元:
Homotetramer; disulfide-linked.


功能:
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.


亚细胞位置:
Secreted


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