ACACA (基因名), Acetyl-CoA carboxylase 1 (蛋白名), acaca_human.
产品名称:
ACACA Antibody
乙酰辅酶A羧化酶1
货号:
M1284Rb-h
商标:
EIAab®
监管等级:
别名:
Acetyl-Coenzyme A carboxylase alpha, ACC-alpha, ACC1, ACAC, ACC1, ACCA
反应性:
human
免疫原:
Recombinant human ACACA protein ( R1284h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Monoclonal
亚型:
Mouse IgG
应用:
推荐产品:
研究领域:
Metabolism
R&D 技术数据
更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.
通用注释
亚单元:
Monomer, homodimer, and homotetramer (PubMed:20952656). Can form filamentous polymers (PubMed:20457939, PubMed:20952656). Interacts in its inactive phosphorylated form with the BRCT domains of BRCA1 which prevents ACACA dephosphorylation and inhibits lipid synthesis (PubMed:12360400, PubMed:16326698). Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity (PubMed:20457939).
功能:
Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA, a key metabolite in the fatty acid synthetic (PubMed:20952656, PubMed:20457939). Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (PubMed:20952656, PubMed:20457939).
亚细胞位置:
Cytoplasm
数据库链接
验证序列:
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