ANGPT2 (基因名), Angiopoietin-2 (蛋白名), angp2_human.
产品名称:
ANGPT2 Antibody
血管生成素
货号:
M0009Rb-h
商标:
EIAab®
监管等级:
别名:
ANG-2
反应性:
human
免疫原:
corresponding to a sequence mapping at the 275-495aa of O15123
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Monoclonal
亚型:
Mouse IgG
应用:
推荐产品:
研究领域:
-
R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释
亚单元:
Interacts with TEK/TIE2, competing for the same binding site as ANGPT1.
功能:
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
亚细胞位置:
Secreted
[1].
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