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BCL11A (基因名), B-cell lymphoma/leukemia 11A (蛋白名), bc11a_human.

产品名称:

BCL11A Antibody
b细胞淋巴瘤/白血病11

货号:

M14965Rb

商标:

EIAab^®

监管等级:

RUO

别名:

B-cell CLL/lymphoma 11A, COUP-TF-interacting protein 1, Ecotropic viral integration site 9 protein homolog, Zinc finger protein 856, EVI-9, BCL-11A, CTIP1, EVI9, KIAA1809, ZNF856

反应性:

human,mouse,rat

免疫原:

Recombinant human BCL11A protein ( R14965h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Monoclonal

亚型:

Mouse IgG

应用:

推荐产品:

Goat Anti-Mouse IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human BCL11A Monoclonal Antibody

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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

通用注释

亚单元:

Interacts with TFCOUP1, PIAS3, ARP1 and EAR2 (By similarity). Isoform 1, isoform 2 and isoform 3 form homodimers and heterodimers (PubMed:27453576).

功能:

Transcription factor associated with the BAF SWI/SNF chromatin remodeling complex (By similarity). Repressor of fetal hemoglobin (HbF) level (PubMed:26375765). Involved in brain development (PubMed:27453576). Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. Essential factor in lymphopoiesis required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.

亚细胞位置:

Isoform 3 Cytoplasm Nucleus Predominantly localized in the cytoplasm in the absence of interaction with isoform 1 and isoform 2. In presence of isoform 1 or isoform 2, translocates from the cytoplasm into nuclear paraspeckles.

数据库链接

UniGene:

Hs.370549

SMR:

Q9H165

STRING:

9606.ENSP00000338774

KEGG:

hsa:53335

MIM:

142335

Uniprot: