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CD33 (基因名), Myeloid cell surface antigen CD33 (蛋白名), cd33_human.

产品名称:

CD33 Antibody
髓系细胞表面抗原CD33

货号:

M15134Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Sialic acid-binding Ig-like lectin 3, gp67, Siglec-3, CD33, SIGLEC3

反应性:

human

免疫原:

Recombinant human CD33 protein ( R15134h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Monoclonal

亚型:

Mouse IgG

应用:

推荐产品:

Goat Anti-Mouse IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human CD33 Monoclonal Antibody

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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

通用注释

亚单元:

Interacts with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation.

功能:

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

亚细胞位置:

Cell membrane Single-pass type I membrane protein

数据库链接

UniGene:

Hs.83731

SMR:

P20138

STRING:

9606.ENSP00000262262

KEGG:

hsa:945

MIM: