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IL31RA (基因名), Interleukin-31 receptor subunit alpha (蛋白名), il31r_human.

产品名称:

IL31RA Antibody
白细胞介素-31受体亚单位

货号:

M0331Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Cytokine receptor-like 3, GLM-R, Gp130-like monocyte receptor, ZcytoR17, hGLM-R, Gp130-like receptor, UNQ6368/PRO21073/PRO21384, IL-31 receptor subunit alpha, CRL3, GPL

反应性:

human

免疫原:

Recombinant human IL31RA protein ( R0331h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Monoclonal

亚型:

Mouse IgG

应用:

推荐产品:

Goat Anti-Mouse IgG(H+L) HRP-conjugated Antibody

研究领域:

Immunology

规格 & 价格:

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Human IL31RA Monoclonal Antibody

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通用注释

亚单元:

Heterodimer with OSMR. Interacts with JAK1 and STAT3.

功能:

Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.

亚细胞位置:

Cell membrane Single-pass type I membrane protein Cell junction Synapse Presynaptic cell membrane Cell projection Axon

数据库链接

UniGene:

Hs.55378

SMR:

Q8NI17

STRING:

9606.ENSP00000415900

KEGG:

hsa:133396

MIM: