首页 > 单抗 > KRT18 Antibody

KRT18 (基因名), Keratin, type I cytoskeletal 18 (蛋白名), k1c18_human.

产品名称:

KRT18 Antibody
角蛋白细胞骨架18型

货号:

M1231Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Cell proliferation-inducing gene 46 protein, Cytokeratin-18, Keratin-18, CK-18, K18, PIG46, CYK18

反应性:

human

免疫原:

corresponding to a sequence mapping at the 243-391aa of P05783

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Monoclonal

亚型:

Mouse IgG

应用:

推荐产品:

Goat Anti-Mouse IgG(H+L) HRP-conjugated Antibody

研究领域:

Epigenetics

规格 & 价格:

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Human KRT18 Monoclonal Antibody

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R&D 技术数据

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通用注释

亚单元:

Heterotetramer of two type I and two type II keratins. KRT18 associates with KRT8. Interacts with the thrombin-antithrombin complex (By similarity). Interacts with PNN, HCV core protein and mutated CFTR. Interacts with YWHAE, YWHAH and YWHAZ only when phosphorylated. Interacts with DNAJB6, TCHP and TRADD. Interacts with FAM83H (PubMed:23902688). Interacts with EPPK1.

功能:

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

亚细胞位置:

Cytoplasm Perinuclear region Nucleus Nucleolus

数据库链接

UniGene:

Hs.406013

SMR:

P05783

STRING:

9606.ENSP00000373487

KEGG:

hsa:3875

MIM: