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KRT1 (基因名), Keratin, type II cytoskeletal 1 (蛋白名), k2c1_human.

产品名称:

KRT1 Antibody
角蛋白II型细胞支架1

货号:

M2282Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

67 kDa cytokeratin, Cytokeratin-1, Hair alpha protein, Keratin-1, Type-II keratin Kb1, CK-1, K1, KRTA

反应性:

human

免疫原:

Recombinant human KRT1 protein ( R2282h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Monoclonal

亚型:

Mouse IgG

应用:

推荐产品:

Goat Anti-Mouse IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human KRT1 Monoclonal Antibody

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R&D 技术数据

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通用注释

亚单元:

Heterotetramer of two type I and two type II keratins. Keratin-1 is generally associated with keratin-10. Interacts with ITGB1 in the presence of RACK1 and SRC, and with RACK1. Interacts with C1QBP; the association represents a cell surface kininogen receptor. Interacts with EPPK1; interaction is dependent of higher-order structure of intermediate filament (PubMed:16923132).

功能:

May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.

亚细胞位置:

Cell membrane Located on plasma membrane of neuroblastoma NMB7 cells.

数据库链接

UniGene:

Hs.80828

SMR:

P04264

STRING:

9606.ENSP00000252244

KEGG:

hsa:3848

MIM: