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LAMP2 (基因名), Lysosome-associated membrane glycoprotein 2 (蛋白名), lamp2_human.

产品名称:

LAMP2 Antibody
溶酶体相关膜糖蛋白2

货号:

M1464Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

CD107 antigen-like family member B, LGP-96, CD107b, LAMP-2

反应性:

Human

免疫原:

Recombinant human LAMP2 protein ( R1464H )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Monoclonal

亚型:

Mouse IgG

应用:

推荐产品:

Goat Anti-Mouse IgG(H+L) HRP-conjugated Antibody

研究领域:

Cardiovascular

规格 & 价格:

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Human LAMP2 Monoclonal Antibody

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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

通用注释

亚单元:

Monomer (PubMed:18644871, PubMed:25342746). Homodimer (PubMed:25342746). Homotrimer (PubMed:25342746). Forms large homooligomers (PubMed:18644871). Interacts (via its cytoplasmic region) with HSPA8 (PubMed:25342746). Interacts with HSP90 in the lysosome lumen; this enhances LAMP2 stability (By similarity). Interacts with MLLT11 (PubMed:24880125).

功能:

Isoform LAMP-2C: Modulates chaperone-mediated autophagy. Decreases presentation of endogenous antigens by MHCII. Does not play a role in the presentation of exogenous and membrane-derived antigens by MHCII.

亚细胞位置:

Cell membrane Single-pass type I membrane protein Endosome membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein Cytoplasmic vesicle Autophagosome membrane This protein shuttles between lysosomes, endosomes, and the plasma membrane.

数据库链接

UniGene:

Hs.496684

SMR:

P13473

KEGG:

hsa:3920

MIM:

300257

Pfam:

PF01299

Uniprot: