PLA2G2A (基因名), Phospholipase A2, membrane associated (蛋白名), pa2ga_human.
产品名称:
PLA2G2A Antibody
膜相关磷脂酶A2
货号:
M8968Rb
商标:
EIAab®
监管等级:
别名:
GIIC sPLA2, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2, Phosphatidylcholine 2-acylhydrolase 2A, NPS-PLA2, PLA2B, PLA2L, RASF-A
反应性:
human,mouse
免疫原:
Recombinant human PLA2G2A protein ( R8968h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Monoclonal
亚型:
Mouse IgG
应用:
推荐产品:
研究领域:
Cardiovascular
R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释
亚单元:
N/A
功能:
Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
亚细胞位置:
Cell membrane
Peripheral membrane protein
Secreted
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