VLDLR (基因名), Very low-density lipoprotein receptor (蛋白名), vldlr_human.
产品名称:
VLDLR Antibody
极低密度脂蛋白受体
货号:
M1009Rb
商标:
EIAab®
监管等级:
别名:
VLDL receptor
反应性:
human,mouse,rat
免疫原:
Recombinant human VLDLR protein ( R1009h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Monoclonal
亚型:
Mouse IgG
应用:
推荐产品:
研究领域:
Cardiovascular
R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释
亚单元:
Binds to the extracellular matrix protein Reelin. Interacts with VLDLR. Interacts with SNX17 (By similarity). Interacts with DAB1. Receptor for the minor-group human rhinoviruses (HRVs); binds protein VP1 through the second and third LDL-receptor class A domains. Interacts with PCSK9.
功能:
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.
亚细胞位置:
Membrane
Single-pass type I membrane protein
Membrane
Clathrin-coated pit
Single-pass type I membrane protein
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