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ATG5 (基因名), Autophagy protein 5 (蛋白名), atg5_human.

产品名称:

ATG5 Antibody

货号:

P15032Rb

商标:

EIAab^®

监管等级:

RUO

别名:

APG5-like, Apoptosis-specific protein, APG5L, ASP

序列号:

Q9H1Y0

反应性:

human,mouse,rat

免疫原:

Recombinant human ATG5 protein ( R15032h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cancer

规格 & 价格:

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Human ATG5 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

mmunohistochemistry: Staining of hepatocytes using ATG5 antibody at 2.5μg/ml. Human liver hepatocytes 40X magnification.

通用注释

亚单元:

Forms a conjugate with ATG12. The ATG5-ATG12 conjugate forms a complex with several units of ATG16L. Interacts with TECPR1; the interaction is direct and does not take place when ATG16L is associated with the ATG5-ATG12 conjugate. ATG12-ATG5 interacts with MAVS, MGA and RARRES3. Interacts with ATG3, ATG7 and ATG10. Interacts with FADD. Interacts transiently interacts with hepatitis C virus (HCV) protein NS5B during HCV infection.

功能:

May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.

亚细胞位置:

Cytoplasm Preautophagosomal structure membrane Peripheral membrane protein Colocalizes with nonmuscle actin. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.

数据库链接

UniGene:

Hs.486063

SMR:

Q9H1Y0

STRING:

9606.ENSP00000343313

KEGG:

hsa:9474

MIM:

604261

Pfam: