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BMP10 (基因名), Bone morphogenetic protein 10 (蛋白名), bmp10_human.
产品名称:

BMP10 Antibody

货号:

P1115Rb-h

商标:
EIAab®
监管等级:
别名:

BMP-10

序列号:
O95393
反应性:
human
免疫原:
corresponding to a sequence mapping at the Recombinant protein of O95393
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
  • Human BMP10 Polyclonal Antibody
  • Human BMP10 Polyclonal Antibody
  • Human BMP10 Polyclonal Antibody
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Human BMP10 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human BMP10 Polyclonal Antibody
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using BMP10 antibody at 1:250 dilution.
通用注释


亚单元:
Homodimer; disulfide-linked (By similarity). Interacts with FBN1 (via N-terminal domain) and FBN2 (PubMed:18339631).


功能:
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。
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