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CASP9 (基因名), Caspase-9 (蛋白名), casp9_human.
产品名称:

CASP9 Antibody

货号:

P0627Rb-h

商标:
EIAab®
监管等级:
别名:

Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, APAF-3, ICE-LAP6, CASP-9, MCH6

序列号:
P55211
反应性:
human
免疫原:
corresponding to a sequence mapping at the 1-260aa of P55211
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Neurosciences
Human CASP9 Polyclonal Antibody
规格 & 价格: cart
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Human CASP9 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
CASP9 antibody detects CASP9 protein at cytoplasm and nucleus in human lung cancer by immunohistochemical analysis.
通用注释


亚单元:
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 35 kDa (p35) and a 10 kDa (p10) subunit. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome C and ATP. Interacts (inactive form) with EFHD2. Interacts with HAX1. Interacts with BIRC2/c-IAP1, XIAP/BIRC4, BIRC5/survivin, BIRC6/bruce and BIRC7/livin. Interacts with ABL1 (via SH3 domain); the interaction is direct and increases in the response of cells to genotoxic stress and ABL1/c-Abl activation. Interacts with NleF from pathogenic E.coli.


功能:
Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。
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