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CHI3L1 (基因名), Chitinase-3-like protein 1 (蛋白名), ch3l1_human.

产品名称:

CHI3L1 Antibody

货号:

P1463Rb

商标:

EIAab^®

监管等级:

RUO

别名:

39 kDa synovial protein, Cartilage glycoprotein 39, YKL-40, CGP-39

序列号:

P36222

反应性:

human,mouse,rat

免疫原:

Recombinant human CHI3L1 protein ( R1463h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Signal Transduction

规格 & 价格:

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Human CHI3L1 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohistochemistry of Human thyroid cancer using CHI3L1 Polyclonal Antibody at dilution of 1:20.

通用注释

亚单元:

Monomer.

功能:

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

亚细胞位置:

Secreted Extracellular space Cytoplasm Cytoplasm Perinuclear region Endoplasmic reticulum

数据库链接

UniGene:

Hs.382202

SMR:

P36222

STRING:

9606.ENSP00000255409

KEGG:

hsa:1116

MIM: