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DEFB126 (基因名), Beta-defensin 126 (蛋白名), db126_human.

产品名称:

DEFB126 Antibody

货号:

P2040Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Beta-defensin 26, Defensin, beta 126, Epididymal secretory protein 13.2, HBD26, DEFB-26, ESP13.2, C20orf8, DEFB26

序列号:

Q9BYW3

反应性:

human

免疫原:

Recombinant human DEFB126 protein ( R2040h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human DEFB126 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

通用注释

亚单元:

Homodimer or homooligomer; disulfide-linked.

功能:

Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte (By similarity). In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (PubMed:19373462, PubMed:23229569).

亚细胞位置:

Secreted Secreted by epididymal cells and is absorbed to the surface of sperm during transit through the epididymis (By similarity). Mainly located on the sperm acrosome.

数据库链接

UniGene:

Hs.124211

STRING:

9606.ENSP00000371835

KEGG:

hsa:81623

Pfam:

PF13841

Uniprot:

Q9BYW3

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