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MLYCD (基因名), Malonyl-CoA decarboxylase, mitochondrial (蛋白名), dcmc_human.

产品名称:

MLYCD Antibody

货号:

P9335Rb

商标:

EIAab^®

监管等级:

RUO

别名:

MCD

序列号:

O95822

反应性:

human,mouse,rat

免疫原:

Recombinant human MLYCD protein ( R9335h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human MLYCD Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohistochemical of paraffin-embedded human kidney using MLYCD antibody at dilution of 1:150.

通用注释

亚单元:

Homotetramer. Dimer of dimers. The two subunits within a dimer display conformational differences suggesting that at any given moment, only one of the two subunits is competent for malonyl-CoA binding and catalytic activity. Under oxidizing conditions, can form disulfide-linked homotetramers (in vitro). Associates with the peroxisomal targeting signal receptor PEX5.

功能:

Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling. May play a role in controlling the extent of ischemic injury by promoting glucose oxidation.

亚细胞位置:

Cytoplasm Mitochondrion matrix Peroxisome Peroxisome matrix Enzymatically active in all three subcellular compartments.

数据库链接

UniGene:

Hs.644610

SMR:

O95822

STRING:

9606.ENSP00000262430

KEGG:

hsa:23417

MIM: