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DLL4 (基因名), Delta-like protein 4 (蛋白名), dll4_human.
产品名称:

DLL4 Antibody

货号:

P13896Rb

商标:
EIAab®
监管等级:
别名:

Drosophila Delta homolog 4, Delta4, UNQ1895/PRO4341

序列号:
Q9NR61
反应性:
human, mouse
免疫原:
corresponding to a sequence mapping at the Recombinant Protein of Q9NR61
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human DLL4 Polyclonal Antibody
规格 & 价格: cart
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Human DLL4 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells.
通用注释


亚单元:
Interacts with NOTCH4. Interacts (via N-terminal DSL and MNNL domains) with NOTCH1 (via EGF-like domains).


功能:
Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344).


亚细胞位置:
Cell membrane Single-pass type I membrane protein


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