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DNM2 (基因名), Dynamin-2 (蛋白名), dyn2_human.
产品名称:

DNM2 Antibody

货号:

P1164Rb

商标:
EIAab®
监管等级:
别名:

DYN2

序列号:
P50570
反应性:
human,mouse,rat
免疫原:
Recombinant human DNM2 protein ( R1164h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human DNM2 Polyclonal Antibody
规格 & 价格: cart
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Human DNM2 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical analysis of paraffin-embedded human breast cancer, using DNM2 antibody at 1:400 dilution.
通用注释


亚单元:
Interacts with MYOF (By similarity). Interacts with CTTN and ACTN1 (By similarity). Interacts with SHANK1, SHANK2, SH3BP4 and NOSTRIN. Interacts with SNX9. Interacts with SNX33 (via SH3 domain). Interacts with MYO1E (via SH3 domain). Interacts with PSTPIP1. Interacts with CTNND2 (PubMed:22022388). May interact with PIK3C3 (By similarity). May be a component of a complex composed of RAB5A (in GDP-bound form), DYN2 and PIK3C3.


功能:
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis (PubMed:12498685). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane.


亚细胞位置:
Cytoplasm Cytoplasm Cytoskeleton Cell junction Membrane Clathrin-coated pit Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cell junction Synapse Midbody Cell projection Phagocytic cup Cytoplasmic vesicle Phagosome membrane Peripheral membrane protein Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (By similarity). Microtubule-associated. Also found in the postsynaptic density of neuronal cells. Co-localizes with PIK3C3 and RAB5A to the nascent phagosome (By similarity).


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