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EEF1A1 (基因名), Elongation factor 1-alpha 1 (蛋白名), ef1a1_human.

产品名称:

EEF1A1 Antibody

货号:

P11476Rb

商标:

EIAab^®

监管等级:

RUO

别名:

Elongation factor Tu, Eukaryotic elongation factor 1 A-1, Leukocyte receptor cluster member 7, EF-Tu, eEF1A-1, EF-1-alpha-1, EEF1A, EF1A, LENG7

序列号:

P68104

反应性:

human, mouse, rat

免疫原:

Recombinant human EEF1A1 protein ( R11476h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Epigenetics

规格 & 价格:

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Human EEF1A1 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohistochemical of paraffin-embedded human pancreas cancer using EEF1A1 antibody at dilution of 1:200

通用注释

亚单元:

Found in a nuclear export complex with XPO5, EEF1A1, Ran and aminoacylated tRNA. Interacts with PARP1, TXK, XPO5 and KARS. May interact with ERGIC2. Interacts with IFIT1 (via TPR repeats 4-7) (By similarity). Interacts with DLC1, facilitating distribution to the membrane periphery and ruffles upon growth factor stimulation. Interacts with ZPR1; the interaction occurs in a epidermal growth factor (EGF)-dependent manner.

功能:

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.

亚细胞位置:

Cytoplasm Nucleus Nucleus Nucleolus Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens.

数据库链接

UniGene:

Hs.535192

SMR:

P68104

STRING:

9606.ENSP00000330054

KEGG:

hsa:1915

MIM:

130590

Pfam: