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EIF3A (基因名), Eukaryotic translation initiation factor 3 subunit A (蛋白名), eif3a_human.
产品名称:

EIF3A Antibody

货号:

P1885Rb-h

商标:
EIAab®
监管等级:
别名:

Eukaryotic translation initiation factor 3 subunit 10, eIF-3-theta, eIF3 p167, eIF3 p180, eIF3 p185, eIF3a, EIF3S10, KIAA0139

序列号:
Q14152
反应性:
Human
免疫原:
Recombinant human EIF3A protein ( R1885H )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Epigenetics
Human EIF3A Polyclonal Antibody
规格 & 价格: cart
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Human EIF3A Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical analysis of paraffinembedded human hepatoma, using EIF3A antibody at 1:200 dilution.
通用注释


亚单元:
Interacts with EIF4G1 (By similarity). Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Also interacts with KRT7 and PIWIL2.


功能:
(Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。
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