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EPHB4 (基因名), Ephrin type-B receptor 4 (蛋白名), ephb4_human.
产品名称:

EPHB4 Antibody

货号:

P15039Rb

商标:
EIAab®
监管等级:
别名:

Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11, HTK, MYK1, TYRO11

序列号:
P54760
反应性:
human,mouse,rat
免疫原:
Recombinant human EPHB4 protein ( R15039h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human EPHB4 Polyclonal Antibody
规格 & 价格: cart
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Human EPHB4 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical of paraffin-embedded human placenta using EPHB4 antibody at dilution of 1:100
通用注释


亚单元:
Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses.


功能:
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.


亚细胞位置:
Cell membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。
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