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FAF2 (基因名), FAS-associated factor 2 (蛋白名), faf2_human.
产品名称:

FAF2 Antibody

货号:

P6959Rb

商标:
EIAab®
监管等级:
别名:

Protein ETEA, UBX domain-containing protein 3B, UBX domain-containing protein 8, ETEA, KIAA0887, UBXD8, UBXN3B

序列号:
Q96CS3
反应性:
human,mouse,rat
免疫原:
Recombinant human FAF2 protein ( R6959h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human FAF2 Polyclonal Antibody
规格 & 价格: cart
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Human FAF2 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
FAF2 antibody detects FAF2 protein at cytoplasm on mouse intestine by immunohistochemical analysis. Sample:Paraffin-embedded mouse intestine.
通用注释


亚单元:
Identified in a complex that contains SEL1L, OS9, FAF2/UBXD8, UBE2J1/UBC6E and AUP1 (PubMed:18711132). Interacts with YOD1 (PubMed:19818707). Interacts (via N-terminus) with UBQLN2 (via C-terminus) (PubMed:24215460). Interacts with PNPLA2 and UBAC2 (PubMed:23297223).


功能:
Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis (PubMed:23297223).


亚细胞位置:
Cytoplasm Lipid droplet Endoplasmic reticulum


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