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FBLN5 (基因名), Fibulin-5 (蛋白名), fbln5_human.

产品名称:

FBLN5 Antibody

货号:

P0209Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Developmental arteries and neural crest EGF-like protein, Urine p50 protein, Dance, UP50, UNQ184/PRO210, FIBL-5, DANCE

序列号:

Q9UBX5

反应性:

human

免疫原:

corresponding to a sequence mapping at the recombinant protein of Q9UBX5

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Signal Transduction

规格 & 价格:

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Human FBLN5 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohistochemical staining of human smooth muscle shows cytoplasmic positivity in smooth muscle cells

通用注释

亚单元:

Homodimer (PubMed:20007835). Monomer (PubMed:15790312, PubMed:19617354), homodimerizes in presence of Ca(2+) (PubMed:19617354). Interacts with ELN (PubMed:17035250, PubMed:15790312). Interacts (via N-terminus) with the integrins ITGAV/ITGB3, ITGAV/ITGB5 and ITGA9/ITGB1 (By similarity). Interacts with FBN1 (via N-terminal domain). Forms a ternary complex with ELN and FBN1 (PubMed:17255108).

功能:

Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823). May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108).

亚细胞位置:

Secreted Secreted Extracellular space Extracellular matrix co-localizes with ELN in elastic fibers.

数据库链接

UniGene:

Hs.332708

SMR:

Q9UBX5

STRING:

9606.ENSP00000345008

KEGG:

hsa:10516

MIM: