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FERMT1 (基因名), Fermitin family homolog 1 (蛋白名), ferm1_human.
产品名称:

FERMT1 Antibody

货号:

P14765Rb

商标:
EIAab®
监管等级:
别名:

Kindlerin, Kindlin syndrome protein, Kindlin-1, Unc-112-related protein 1, C20orf42, KIND1, URP1

序列号:
Q9BQL6
反应性:
human, mouse
免疫原:
Recombinant human FERMT1 protein ( R14765h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human FERMT1 Polyclonal Antibody
规格 & 价格: cart
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Human FERMT1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemistry of formalinfixed, paraffin-embedded tissue. Antibody FERMT1 dilution 1:200.
通用注释


亚单元:
Interacts with the cytoplasmic domain of integrins ITGB1 and ITGB3.


功能:
Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.


亚细胞位置:
Cytoplasm Cytoskeleton Cell junction Focal adhesion Cell projection Ruffle membrane Peripheral membrane protein Cytoplasmic side Constituent of focal adhesions. Localized at the basal aspect of skin keratinocytes, close to the cell membrane. Colocalizes with filamentous actin. Upon TGFB1 treatment, it localizes to membrane ruffles.


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