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FGL1 (基因名), Fibrinogen-like protein 1 (蛋白名), fgl1_human.
产品名称:

FGL1 Antibody

货号:

P15163Rb

商标:
EIAab®
监管等级:
别名:

HP-041, Hepassocin, Hepatocyte-derived fibrinogen-related protein 1, Liver fibrinogen-related protein 1, HPS, HFREP-1, LFIRE-1, HFREP1

序列号:
Q08830
反应性:
human,mouse,rat
免疫原:
Recombinant human FGL1 protein ( R15163h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human FGL1 Polyclonal Antibody
规格 & 价格: cart
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Human FGL1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemistry of Human liver cancer using FGL1 Antibody at dilution of 1:100.
通用注释


亚单元:
Homodimer (PubMed:11470158). Interacts (via the Fibrinogen C-terminal domain) with LAG3 (via Ig-like domains 1 and 2) (PubMed:30580966).


功能:
Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed:30580966). Responsible for LAG3 T-cell inhibitory function (PubMed:30580966). Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966). In addition to its role in inhibiting inflammatory immune responses, also plays a role in hepatocytes (PubMed:11470158, PubMed:19880967). Under normal physiological conditions, primarily secreted from hepatocytes and contributes to its mitogenic and metabolic functions (PubMed:11470158, PubMed:19880967).


亚细胞位置:
Secreted Secreted in the blood plasma.


该产品尚未在任何出版物中被引用。
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