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FSTL3 (基因名), Follistatin-related protein 3 (蛋白名), fstl3_human.

产品名称:

FSTL3 Antibody

货号:

P0127Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Follistatin-like protein 3, Follistatin-related gene protein, UNQ674/PRO1308, FLRG

序列号:

O95633

反应性:

human

免疫原:

Recombinant human FSTL3 protein ( R0127h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Signal Transduction

规格 & 价格:

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Human FSTL3 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

FSTL3 Antibody immunohistochemistry of formalin-fixed and paraffin- embedded human testis tissue

通用注释

亚单元:

Interacts with INHBA and INHBB. Interacts with FN1. Interacts with ADAM12. Isoform 2 interacts with MLLT10; the interaction enhances MLLT10 in vitro transcriptional activity and self-association. Interacts with MSTN.

功能:

Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.

亚细胞位置:

Isoform 2 Nucleus Although alternative initiation has been demonstrated and resulted in different localization, the major source of nuclear FSTL3 appears not to depend on translation initiation at Met-27 according to.

数据库链接

UniGene:

Hs.529038

SMR:

O95633

STRING:

9606.ENSP00000166139

KEGG:

hsa:10272

MIM:

605343

Pfam: