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GNAS (基因名), Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (蛋白名), gnas1_human.
产品名称:

GNAS Antibody

货号:

P14288Rb-h

商标:
EIAab®
监管等级:
别名:

Adenylate cyclase-stimulating G alpha protein, Extra large alphas protein, XLalphas, GNAS1

序列号:
Q5JWF2
反应性:
Human
免疫原:
corresponding to a sequence mapping at the 11-230aa of Q5JWF2
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
推荐产品:
研究领域:
Neurosciences
Human GNAS Polyclonal Antibody
规格 & 价格: cart
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Human GNAS Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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R&D 技术数据
Human GNAS Polyclonal Antibody
293T lysate was subjected to SDS-PAGE followed by Western Blot with GNAS antibody at dilution of 1:300 (Observed molecular weight is about 45kDa)
通用注释


亚单元:
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts through its N-terminal region with ALEX which is produced from the same locus in a different open reading frame. This interaction may inhibit its adenylyl cyclase-stimulating activity (By similarity). Interacts with MAGED2 (PubMed:27120771).


功能:
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms.


亚细胞位置:
Cell membrane Peripheral membrane protein Apical cell membrane


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