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H3F3A (基因名), Histone H3.3 (蛋白名), h33_human.

产品名称:

H3F3A Antibody

货号:

P5810Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

PP781, H3.3A, H3F3

序列号:

P84243

反应性:

human

免疫原:

Recombinant human H3F3A Protein (R5810h)

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human H3F3A Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Mouse lung tissue lysate was subjected to SDS-PAGE followed by Western Blot with H3F3A antibody at dilution of 1:300 (Observed molecular weight is about70 kDa)

通用注释

亚单元:

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Interacts with HIRA, a chaperone required for its incorporation into nucleosomes. Interacts with ZMYND11; when trimethylated at 'Lys-36' (H3.3K36me3).

功能:

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

亚细胞位置:

Nucleus Chromosome

数据库链接

UniGene:

Hs.180877

SMR:

P84243

STRING:

9606.ENSP00000355778

KEGG:

hsa:3020

MIM: