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HTT (基因名), Huntingtin (蛋白名), hd_human.
产品名称:

HTT Antibody

货号:

P1166Rb-h

商标:
EIAab®
监管等级:
别名:

Huntington disease protein, HD protein, HD, IT15

序列号:
P42858
反应性:
human
免疫原:
( )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Neurosciences
Human HTT Polyclonal Antibody
规格 & 价格: cart
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Human HTT Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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R&D 技术数据
HTT antibody detects HTT protein at cytoplasm in rat brain by immunohistochemical analysis.
通用注释


亚单元:
Interacts with PFN1 (PubMed:18573880). Interacts through its N-terminus with PRPF40A (PubMed:9700202). Interacts with PQBP1 (PubMed:10332029). Interacts with SETD2 (PubMed:9700202, PubMed:10958656, PubMed:11461154). Interacts with SH3GLB1 (By similarity). Interacts with SYVN (PubMed:17141218). Interacts with TPR; the interaction is inhibited by forms of Huntingtin with expanded polyglutamine stretch (PubMed:15654337). Interacts with ZDHHC13 (via ANK repeats) (PubMed:26198635). Interacts with ZDHHC17 (via ANK repeats) (PubMed:26198635).


功能:
May play a role in microtubule-mediated transport or vesicle function.


亚细胞位置:
Cytoplasm Nucleus The mutant Huntingtin protein colocalizes with AKAP8L in the nuclear matrix of Huntington disease neurons. Shuttles between cytoplasm and nucleus in a Ran GTPase-independent manner.


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