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HSPA6 (基因名), Heat shock 70 kDa protein 6 (蛋白名), hsp76_human.
产品名称:

HSPA6 Antibody

货号:

P1089Rb

商标:
EIAab®
监管等级:
别名:

Heat shock 70 kDa protein B', HSP70B'

序列号:
P17066
反应性:
human,mouse,rat
免疫原:
Recombinant human HSPA6 protein ( R1089h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human HSPA6 Polyclonal Antibody
规格 & 价格: cart
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Human HSPA6 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical analysis of formalin-fixed and paraffin-embedded using HSPA6 antibody.
通用注释


亚单元:
N/A


功能:
Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed:26865365).


亚细胞位置:
N/A


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