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HSPB1 (基因名), Heat shock protein beta-1 (蛋白名), hspb1_human.

产品名称:

HSPB1 Antibody

货号:

P0693Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, Stress-responsive protein 27, HSP 27, SRP27, HspB1, HSP27, HSP28

序列号:

P04792

反应性:

human

免疫原:

Recombinant human HSPB1 Protein (R0693h)

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Epigenetics

规格 & 价格:

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Human HSPB1 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

HSPB1 antibody detects HSPB1 protein at cytoplasm in human ung papillary carcinoma by immunohistochemical analysis.

通用注释

亚单元:

Homooligomer (PubMed:10383393). Homodimer; becomes monomeric upon activation (PubMed:20178975). Heterooligomer; with HSPB6 (PubMed:23948568). Associates with alpha- and beta-tubulin (PubMed:10777697). Interacts with TGFB1I1 (By similarity). Interacts with CRYAB (PubMed:1560006). Interacts with HSPB8 (PubMed:11342557). Interacts with HSPBAP1 (PubMed:10751411).

功能:

Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).

亚细胞位置:

Cytoplasm Nucleus Cytoplasm Cytoskeleton Spindle Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.

数据库链接

UniGene:

Hs.520973

SMR:

P04792

STRING:

9606.ENSP00000248553

KEGG:

hsa:3315

MIM:

602195

Pfam: