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IL12B (基因名), Interleukin-12 subunit beta (蛋白名), il12b_human.

产品名称:

IL12B Antibody

货号:

P0058Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, NK cell stimulatory factor chain 2, CLMF p40, NKSF2, IL-12B, NKSF2

序列号:

P29460

反应性:

human

免疫原:

Recombinant human IL12B protein ( R0058h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Immunology

规格 & 价格:

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Human IL12B Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

ImmunohistochemistryParaffin IL12B Antibody Staining of human small intestine shows strong cytoplasmic positivity in lymphoid cells.

通用注释

亚单元:

Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12. Heterodimer with IL23A; disulfide-linked. The heterodimer is known as interleukin IL-23. Also secreted as a monomer.

功能:

Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

亚细胞位置:

Secreted

数据库链接

UniGene:

Hs.674

SMR:

P29460

STRING:

9606.ENSP00000231228

KEGG:

hsa:3593

MIM: