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ITLN1 (基因名), Intelectin-1 (蛋白名), itln1_human.

产品名称:

ITLN1 Antibody

货号:

P0933Rb

商标:

EIAab^®

监管等级:

RUO

别名:

Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, Omentin, UNQ640/PRO1270, ITLN-1, INTL, ITLN, LFR

序列号:

Q8WWA0

反应性:

human,mouse,rat

免疫原:

corresponding to a sequence mapping at the 19-298aa of Q8WWA0

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cardiovascular

规格 & 价格:

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Human ITLN1 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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数据
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R&D 技术数据

Immunohistochemil of paraffm—embeddecl human small intestine using TLNI antibody at dilution of 1:40

通用注释

亚单元:

Homotrimer; disulfide-linked (PubMed:11313366, PubMed:17621593, PubMed:26148048). May interact with LTF (PubMed:11747454, PubMed:23921499).

功能:

Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed:11313366, PubMed:26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed:26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris (PubMed:26148048). Does not bind human glycans (PubMed:26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed:16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed:16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed:11747454, PubMed:23921499).

亚细胞位置:

Cell membrane Lipid-anchor GPI-anchor Secreted Enriched in lipid rafts.

数据库链接

UniGene:

Hs.50813

SMR:

Q8WWA0

STRING:

9606.ENSP00000323587

KEGG:

hsa:55600

MIM: