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KRT17 (基因名), Keratin, type I cytoskeletal 17 (蛋白名), k1c17_human.

产品名称:

KRT17 Antibody

货号:

P1822Rb

商标:

EIAab^®

监管等级:

RUO

别名:

Cytokeratin-17, Keratin-17, CK-17, K17

序列号:

Q04695

反应性:

human,mouse

免疫原:

Recombinant human KRT17 protein ( R1822h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human KRT17 Polyclonal Antibody

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产品说明书

数据表:

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R&D 技术数据

Immunohistochemical of paraffin-embedded human cervical cancer using KRT17 antibody.

通用注释

亚单元:

Heterodimer of a type I and a type II keratin. KRT17 associates with KRT6 isomers (KRT6A or KRT6B). Interacts with TRADD and SFN (By similarity).

功能:

Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.

亚细胞位置:

Cytoplasm

数据库链接

UniGene:

Hs.2785

SMR:

Q04695

STRING:

9606.ENSP00000308452

KEGG:

hsa:3872

MIM: