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KAT8 (基因名), Histone acetyltransferase KAT8 (蛋白名), kat8_human.

产品名称:

KAT8 Antibody

货号:

P2934Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Lysine acetyltransferase 8, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, PP7073, MOF, MYST1

序列号:

Q9H7Z6

反应性:

human

免疫原:

corresponding to a sequence mapping at the Recombinant protein of Q9H7Z6

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human KAT8 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

在线询价

数据
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R&D 技术数据

Formalin-fixed and paraffm-embedded human breast carcinoma tissue reacted with KAT8 antibody.

通用注释

亚单元:

Component of a multisubunit histone acetyltransferase complex (MSL) at least composed of the MOF/KAT8, MSL1/hampin, MSL2L1 and MSL3L1. Interacts with MSL1; the interaction is direct. Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1. Interacts with KANSL1; the interaction is direct. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MOF/KAT8, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with the chromodomain of MORF4L1/MRG15. Interacts with ATM through the chromodomain. Interacts with KANSL1; the interaction is direct.

功能:

Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'.

亚细胞位置:

Nucleus Chromosome

数据库链接

UniGene:

Hs.533803

SMR:

Q9H7Z6

STRING:

9606.ENSP00000406037

KEGG:

hsa:84148

MIM: