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KISS1R (基因名), KiSS-1 receptor (蛋白名), kissr_human.

产品名称:

KISS1R Antibody

货号:

P2140Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

G-protein coupled receptor 54, G-protein coupled receptor OT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor, hOT7T175, KiSS-1R, AXOR12, GPR54

序列号:

Q969F8

反应性:

human

免疫原:

Recombinant human KISS1R protein ( R2140h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human KISS1R Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohis tochemistry analysis in human placenta and prostate tissues using Anti KISS1 antibody.

通用注释

亚单元:

N/A

功能:

Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

亚细胞位置:

Cell membrane Multi-pass membrane protein

数据库链接

UniGene:

Hs.208229

STRING:

9606.ENSP00000234371

KEGG:

hsa:84634

MIM:

176400

Pfam: