首页 > 一抗 > KLK6 Antibody

KLK6 (基因名), Kallikrein-6 (蛋白名), klk6_human.

产品名称:

KLK6 Antibody

货号:

P0691Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Neurosin, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme, PRSS18, PRSS9

序列号:

Q92876

反应性:

human

免疫原:

Recombinant human KLK6 protein ( R0691h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Neurosciences

规格 & 价格:

关注

Human KLK6 Polyclonal Antibody

邮箱 *

消息 *

Please 登录.

产品说明书

数据表:

MSDS:

在线询价

数据
文献
序列 / 3D
常见问题解答
反馈墙 (0)

R&D 技术数据

IHC-P:KLK6 in Human Breast Cancer Tissue.

通用注释

亚单元:

N/A

功能:

Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

亚细胞位置:

Secreted Nucleus Nucleolus Cytoplasm Mitochondrion Microsome In brain, detected in the nucleus of glial cells and in the nucleus and cytoplasm of neurons. Detected in the mitochondrial and microsomal fractions of HEK-293 cells and released into the cytoplasm following cell stress.

数据库链接

UniGene:

Hs.79361

SMR:

Q92876

STRING:

9606.ENSP00000309148

KEGG:

hsa:5653

MIM:

602652

Pfam: