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LCAT (基因名), Phosphatidylcholine-sterol acyltransferase (蛋白名), lcat_human.

产品名称:

LCAT Antibody

货号:

P2114Rb

商标:

EIAab^®

监管等级:

RUO

别名:

Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase

序列号:

P04180

反应性:

human,mouse,rat

免疫原:

Recombinant human LCAT protein ( R2114h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cardiovascular

规格 & 价格:

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Human LCAT Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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通用注释

亚单元:

N/A

功能:

Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs) (PubMed:10329423, PubMed:19065001, PubMed:26195816). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines (PubMed:8820107). Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms (PubMed:10722751).

亚细胞位置:

Secreted Secreted into blood plasma (PubMed:3458198, PubMed:8820107, PubMed:10222237). Produced in astrocytes and secreted into cerebral spinal fluid (CSF).

数据库链接

UniGene:

Hs.387239

SMR:

P04180

STRING:

9606.ENSP00000264005

KEGG:

hsa:3931

MIM:

136120

Pfam: