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LRPPRC (基因名), Leucine-rich PPR motif-containing protein, mitochondrial (蛋白名), lpprc_human.
产品名称:

LRPPRC Antibody

货号:

P14393Rb

商标:
EIAab®
监管等级:
别名:

130 kDa leucine-rich protein, GP130, LRP 130, LRP130

序列号:
P42704
反应性:
human,mouse,rat
免疫原:
Recombinant human LRPPRC Protein (R14393h)
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Neurosciences
Human LRPPRC Polyclonal Antibody
规格 & 价格: cart
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Human LRPPRC Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Internal detects LRP130 protein at cytoplasm in human colon cancer by immunohistochemical analysis.
通用注释


亚单元:
Interacts with CECR2, HEBP2, MAP1S and UXT. Interacts with PPARGC1A. Interacts with FOXO1 (By similarity). Component of mRNP complexes associated with HNRPA1.


功能:
May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA.


亚细胞位置:
Mitochondrion Nucleus Nucleoplasm Nucleus inner membrane Nucleus outer membrane Seems to be predominantly mitochondrial.


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