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MTDH (基因名), Protein LYRIC (蛋白名), lyric_human.
产品名称:

MTDH Antibody

货号:

P1442Rb-h

商标:
EIAab®
监管等级:
别名:

3D3/LYRIC, Astrocyte elevated gene-1 protein, Lysine-rich CEACAM1 co-isolated protein, Metadherin, Metastasis adhesion protein, AEG-1, AEG1, LYRIC

序列号:
Q86UE4
反应性:
human
免疫原:
Recombinant human MTDH protein ( R1442h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Epigenetics
Human MTDH Polyclonal Antibody
规格 & 价格: cart
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Human MTDH Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical staining of human small intestine using MTDH antibody shows nuclear and cytoplasmic positivity in glandular cells.
通用注释


亚单元:
Interacts with BCCIP, CREBBP/CBP and RELA/p65.


功能:
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.


亚细胞位置:
Endoplasmic reticulum membrane Single-pass membrane protein Nucleus membrane Single-pass membrane protein Cell junction Tight junction Nucleus Nucleolus Cytoplasm Perinuclear region In epithelial cells, recruited to tight junctions (TJ) during the maturation of the TJ complexes. A nucleolar staining may be due to nuclear targeting of an isoform lacking the transmembrane domain (By similarity). TNF-alpha causes translocation from the cytoplasm to the nucleus.


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