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MASP1 (基因名), Mannan-binding lectin serine protease 1 (蛋白名), masp1_human.
产品名称:

MASP1 Antibody

货号:

P1895Rb-h

商标:
EIAab®
监管等级:
别名:

Complement factor MASP-3, Complement-activating component of Ra-reactive factor, Mannose-binding lectin-associated serine protease 1, Mannose-binding protein-associated serine protease, Ra-reactive factor serine protease p100, Serine protease 5, MASP-1, RaRF, CRARF, CRARF1, PRSS5

序列号:
P48740
反应性:
human
免疫原:
Recombinant human MASP1 protein ( R1895h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Immunology
Human MASP1 Polyclonal Antibody
规格 & 价格: cart
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Human MASP1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti- MASP1 Polyclonal Antibody.
通用注释


亚单元:
Homodimer. Interacts with the oligomeric lectins MBL2, FCN2 and FCN3; triggers the lectin pathway of complement through activation of C3. Interacts with SERPING1.


功能:
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。
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