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MNAT1 (基因名), CDK-activating kinase assembly factor MAT1 (蛋白名), mat1_human.
产品名称:

MNAT1 Antibody

货号:

P14238Rb

商标:
EIAab®
监管等级:
别名:

CDK7/cyclin-H assembly factor, Cyclin-G1-interacting protein, Menage a trois, RING finger protein 66, RING finger protein MAT1, p35, p36, CAP35, MAT1, RNF66

序列号:
P51948
反应性:
human,mouse,rat
免疫原:
corresponding to a sequence mapping at the Internal of P51948
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human MNAT1 Polyclonal Antibody
规格 & 价格: cart
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Human MNAT1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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R&D 技术数据
Immunohistochemical analysis of MNAT1 staining in human brain formalin fixed paraffin embedded tissue section.?
通用注释


亚单元:
Associates primarily with CDK7 and cyclin H to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.


功能:
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.


亚细胞位置:
Nucleus


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