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MBP (基因名), Myelin basic protein (蛋白名), mbp_human.
产品名称:

MBP Antibody

货号:

P0539Rb-h

商标:
EIAab®
监管等级:
别名:

Myelin A1 protein, Myelin membrane encephalitogenic protein, MBP

序列号:
P02686
反应性:
human
免疫原:
Recombinant human MBP protein ( R0539h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human MBP Polyclonal Antibody
规格 & 价格: cart
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Human MBP Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
IHC-P: MBP antibody testing of rat brain tissue.
通用注释


亚单元:
Homodimer. Isoform 3 exists as a homodimer.


功能:
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.


亚细胞位置:
Isoform 3 Nucleus Targeted to nucleus in oligodendrocytes.


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